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Third, based on the data presented in this paper, HPL exhibited the potential to restore Anpep expression in the glutathione metabolism pathway and turnover-induced metabolite shift, which reflect the powerful effect of HPL on glutathione redox stress

Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE (2018) Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid- uptake in astrocytes

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Non-targeted lipidomicsinstrumental condition and data analysis The HPLC conditions were identical to the previous study 97